FISH ANALYSIS MDS PANEL

General Information

HLAB/HOL Code: FISH
UPHSM LIS Test #: 5436
Schedule: Monday - Friday
Testing Time: 2 - 5 days
Testing Lab: UP Health System-Marquette

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 3.0 mL Bone Marrow or 5.0 mL Blood
Temperature: Ambient
Tube Type: Sodium heparin Bone Marrow or Malignant Blood tube
Collection Info:
Prefer a minimum of 3.0 mL of bone marrow or 5.0 mL of peripheral blood. Draw into green-top (sodium-heparin) tube(s), invert several times to mix. Clotted specimens may not work and can compromise results. Label vial with patient's name and a unique identifying number. Maximum time from collection should not exceed 24 hrs.
SPECIMENS CANNOT BE FROZEN

Methods

Fluorescence in situ hybridization (FISH) interphase set-up and analysis of 200 cells for EVI1 gene, MLL gene, chromosomes -5/5q-, -7/7q-, +8, -20/20q-.

Clinical Utilities

Detection of abnormalities involving chromosomes -5/5q-, -7/7q-, +8, MLL gene, inversion chromosome 3, and chromosome -20/20q- most commonly associated with myelodysplasia or MDS by FISH

CPT Codes

CALL FOR CPTs

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

An interpretive report will be provided.