IRON LIVER TISSUE

General Information

HLAB/HOL Code: IRNLT
UPHSM LIS Test #: 026974
Schedule:
Testing Time: 3-5 Days
Testing Lab: Mayo

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 2 mg tissue
Temperature: Refrigerate
Tube Type: Liver Tissue
Collection Info:
Preferred: Mayo metal-free specimen vial (blue label)
Acceptable: Paraffin block, if not more than 1 or 2 cuts have been made to it for slides

Collection Instructions:
1. Two mg of liver tissue is required. This is typically a piece of tissue from a 22-gauge needle biopsy at least 2 cm long. If an 18-gauge needle is used, the tissue must be at least 1 cm in length.
2. Any specimen vial other than a Mayo metal-free vial used should be plastic, leached with 10% nitric acid for 2 days, rinsed with redistilled water, and dried in clean air.
Additional Information: Paraffin blocks will be returned 3 days after analysis.

SPECIMEN MINIMUM VOLUME
2 cm (22-gauge needle)
1 cm (18-gauge needle)
2 mm x 2 mm (punch) 0.3 mg by dry weight

Methods

Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

Clinical Utilities

Diagnosis of hemochromatosis using liver tissue specimens

CPT Codes

83540

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

Iron
Males: 200-2400 mcg/g dry weight
Females: 400-1600 mcg/g dry weight

Iron Index
<1.0 mcmol/g/year (> or = 13 Y)