ALPHA-SUBUNIT PITUITARY TUMOR MARKER SERUM

General Information

HLAB/HOL Code: APSUB
UPHSM LIS Test #: 028584
Schedule: Monday
Testing Time: 1-7 Days
Testing Lab: Mayo Labs

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 1.0 mL (0.4 min)
Temperature: Refrigerate
Tube Type: Serum
Collection Info:
This test should not be ordered on pregnant patients.

Methods

immunochemiluminescent assay sandwich procedure

Clinical Utilities

Adjunct in the diagnosis of pituitary tumors
As part of the follow-up of treated pituitary tumor patients
Differential diagnosis of thyrotropin-secreting pituitary tumor versus thyroid hormone resistance
Differential diagnosis of constitutional delay of puberty versus hypogonadotrophic hypogonadism

CPT Codes

82397

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

PEDIATRIC

< or =5 days: < or =50 ng/mL

6 days-12 weeks: < or =10 ng/mL
3 months-17 years: < or =1.2 ng/mL
Tanner II-IV*: < or =1.2 ng/mL

ADULTS
Males: < or =0.5 ng/mL
Premenopausal females: < or =1.2 ng/mL
Postmenopausal females: < or =1.8 ng/mL
Pediatric and adult reference values based on Mayo studies.

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (+/-2) years and for girls at a median age of 10.5 (+/-2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls.
For boys, there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable.
Tanner stage V (adult) should be reached by age 18.