CLOMIPRAMINE SERUM

General Information

HLAB/HOL Code: CLOMP
UPHSM LIS Test #: 026840
Schedule:
Testing Time: 3-5 Days
Testing Lab: Mayo Labs

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 1.0 mL (0.3 min) serum
Temperature: Refrigerate
Tube Type: Serum
Collection Info:
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Draw specimen immediately before next scheduled dose (minimum 12 hours after last dose).
Separate serum from cells within 2 hours of draw.

Specimen Acceptability

REJECT DUE TO:
Gross hemolysis: OK
Gross lipemia: OK
Gross icterus: OK

Methods

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Clinical Utilities

Determining whether a poor therapeutic response is attributable to noncompliance
Monitoring serum concentration of clomipramine and norclomipramine to assist in optimizing the administered dose

CPT Codes

80335
G0480 (if appropriate)

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

Clomipramine and Norclomipramine
Therapeutic concentration: 230-450 ng/mL

Therapeutic ranges are for specimens drawn at trough (ie, immediately before next scheduled dose). Levels may be elevated in non-trough specimens.