ITRACONAZOLE SERUM

General Information

HLAB/HOL Code: ITCNZ
UPHSM LIS Test #: 026174
Schedule:
Testing Time: 1-3 Days
Testing Lab: Mayo

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 1.0 mL Serum
Temperature: Refrigerated
Tube Type: Serum
Collection Info:
Collection Container/Tube: Red top (serum gel/SST are NOT acceptable)
Collection Instructions: Centrifuge and aliquot serum into plastic vial.

Specimen Acceptability

REJECT DUE TO:
Gross hemolysis: OK
Gross lipemia: OK
Gross icterus: OK

Methods

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Clinical Utilities

Verifying systemic absorption of orally administered itraconazole
Patients with life-threatening fungal infections
Patients considered at risk for poor absorption or rapid clearance of itraconazole

CPT Codes

80189

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

ITRACONAZOLE (TROUGH):
>0.5 mcg/mL (localized infection)
>1 mcg/mL (systemic infection)

HYDROXYITRACONAZOLE:
No therapeutic range established; activity and serum concentration are similar to parent drug.