PROTEIN S ACTIVITY

General Information

HLAB/HOL Code: PROTS
UPHSM LIS Test #: 8604
Schedule: Varies
Testing Time: 1 day
Testing Lab: UP Health System-Marquette

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 1.0 mL plasma
Temperature: Frozen
Tube Type: 1 Blue Top (Citrate)
Collection Info:
Do not over/under fill the tube. Immediately centrifuge (double spin) and separate plasma from cells. Aliquot 0.5 mL plasma into separate tubes.

Methods

Photo optical clotting

Clinical Utilities

Diagnosis of congenital protein S deficiency which may increase the risk of thrombosis. An abnormal result should be followed up with protein S antigen, total and free.

CPT Codes

85305

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

0 - 127 Years......60 - 200%

Assay is a clotting test measuring Protein S Activity. Levels may be decreased in pregnancy, vitamin K deficiency, recent surgery, and coumadin (OAT) or L-asparaginase or estrogen therapy. Lupus Anticoagulants may give prolonged results. If result is low, it is recommended that free and total Protein S levels be performed to determine the type of Protein S deficiency.