PROTEIN C ACTIVITY
General Information
HLAB/HOL Code: PROTC
UPHSM LIS Test #: 8614
Schedule: Monday, Wednesday, Friday
Testing Time: 1 day
Testing Lab: UP Health System-Marquette
UPHSM LIS Test #: 8614
Schedule: Monday, Wednesday, Friday
Testing Time: 1 day
Testing Lab: UP Health System-Marquette
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 1.0 mL plasma
Temperature: Frozen
Tube Type: 1 Blue Top (Citrate)
Collection Info:
Do not over/under fill the tube. Immediately centrifuge (double spin 10 min) and separate plasma from cells. Aliquot 0.5 mL plasma into two separate tubes.
Temperature: Frozen
Tube Type: 1 Blue Top (Citrate)
Collection Info:
Do not over/under fill the tube. Immediately centrifuge (double spin 10 min) and separate plasma from cells. Aliquot 0.5 mL plasma into two separate tubes.
Methods
Chromogenic Substrate Assay
Clinical Utilities
Determining the functional activity of Protein C, aiding in the diagnosis of a hypercoagulable disorder. If activity is decreased and differentiation between type 1 and 2 deficiency is desired, a Protein C Antigen should be ordered.
CPT Codes
85303
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
0 - 127 Years.............75 - 176%
Assay is a chromogenic test measuring functional Protein C. An acquired deficiency may be due to recent thrombosis, surgery, DIC, Vitamin K deficiency, and L-asparaginase or oral anticoagulant therapy (OAT). Patients should be off OAT for at least 10 days prior to testing. If result is low, Protein C Antigen is recommended to determine if deficiency is Type I (quantitative) or Type II (qualitative).
Assay is a chromogenic test measuring functional Protein C. An acquired deficiency may be due to recent thrombosis, surgery, DIC, Vitamin K deficiency, and L-asparaginase or oral anticoagulant therapy (OAT). Patients should be off OAT for at least 10 days prior to testing. If result is low, Protein C Antigen is recommended to determine if deficiency is Type I (quantitative) or Type II (qualitative).
