FISH ANALYSIS UROVYSION BLADDER CANCER

General Information

HLAB/HOL Code: FISH
UPHSM LIS Test #: 7008
Schedule: Monday- Friday
Testing Time: 2 - 5 days
Testing Lab: UP Health System-Marquette

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 30 mL
Temperature: Refrigerate
Tube Type: Urine with PreservCyt preservative
Collection Info:
Minimum of 30 mL of voided urine.  Mix voided urine 3:1 (v:v) with PreservCyt preservative.  Refrigerate and ship at temperature up to 25 C within 24 hours of collection.  Specimen CANNOT be frozen.

Methods

Fluorescence in situ hybridization (FISH) processing of urine specimens for UroVysion testing.  Specific probes include chromosome centromeres 3, 7, 17, and p16 locus specific probe for 9p21 are analyzed.

Clinical Utilities

Detection of aneuploidy of chromosomes 3,7, and 17, and loss of 9p21 locus in person with hematuria suspected of having bladder
cancer, to aid in initial diagnosis of bladder cancer, and subsequent monitoring of tumor recurrence in patients previously diagnosed with bladder cancer.

CPT Codes

CALL FOR CPTs

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

An interpretive report will be provided.