FISH ANALYSIS PDGFRB
General Information
HLAB/HOL Code: FISH
UPHSM LIS Test #: 2514
Schedule: Monday - Friday
Testing Time: 2 - 5 days
Testing Lab: UP Health System-Marquette
UPHSM LIS Test #: 2514
Schedule: Monday - Friday
Testing Time: 2 - 5 days
Testing Lab: UP Health System-Marquette
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume:
Temperature: Ambient
Tube Type: Sodium heparin (green top)
Collection Info:
Bone Marrow is the tissue of choice for initial diagnosis of most neoplastic specimens. Malignant blood can be used in certain cases to monitor minimal residual disease. Prefer a minimum of 3.0 mL of bone marrow or 5.0 mL of malignant blood. Draw into green-top (sodium heparin) tube(s), invert several times to mix (clotted specimens may not work and can compromise results). Label vial with the patient's name and a unique identifying number (MGHS encounter # or MR #). Maximum time from collection should not exceed 24 hours.
SPECIMENS CANNOT BE FROZEN
Temperature: Ambient
Tube Type: Sodium heparin (green top)
Collection Info:
Bone Marrow is the tissue of choice for initial diagnosis of most neoplastic specimens. Malignant blood can be used in certain cases to monitor minimal residual disease. Prefer a minimum of 3.0 mL of bone marrow or 5.0 mL of malignant blood. Draw into green-top (sodium heparin) tube(s), invert several times to mix (clotted specimens may not work and can compromise results). Label vial with the patient's name and a unique identifying number (MGHS encounter # or MR #). Maximum time from collection should not exceed 24 hours.
SPECIMENS CANNOT BE FROZEN
Volume: 5.0 mL Blood
Temperature: Ambient
Tube Type: Sodium heparin (green top)
Collection Info:
Temperature: Ambient
Tube Type: Sodium heparin (green top)
Collection Info:
Volume:
Temperature:
Tube Type:
Collection Info:
Temperature:
Tube Type:
Collection Info:
Methods
Fluorescence in situ hybridization (FISH) interphase set-up and analysis for PDGRFB gene. A minimum of 200 interphase nuclei will be analyzed.
Clinical Utilities
Detection of the PDGRFB platelet derived growth factor receptor beta gene disruption associated with Myeloproliferative neoplasm.
CPT Codes
CALL FOR CPTs
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
An interpretive report will be provided.
