NEUROMYELITIS OPTICA IGG AUTOANTIBODIES

General Information

HLAB/HOL Code: NMOCS
UPHSM LIS Test #: 026346
Schedule:
Testing Time: 3-5 Days
Testing Lab: Labcorp

Specimen Info
Only 1 specimen type required, unless otherwise specified

Volume: 0.2 mL Serum
Temperature: Frozen
Tube Type: Serum
Collection Info:
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.

Specimen Acceptability

Causes for Rejection
Gross lipemia; gross hemolysis; gross icterus

Methods

Enzyme-linked immunosorbent assay (ELISA)

Clinical Utilities

Establishing the diagnosis of neuromyelitis optica (NMO) and related disorders, including relapsing transverse myelitis or relapsing optic neuritis. Distinguishing NMO and NMO spectrum disorders from multiple sclerosis early in the course of disease. This test can also be used to trigger initiation and monitor effectiveness of therapy.

Limitations:  Seronegativity does not exclude the diagnosis of NMO. Immunosuppressive therapy may result in negative results. Results for this test are for research purposes only by the assay's manufacturer. The performance characteristics of this product have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.

CPT Codes

86051

* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Reference Range

• 0−3.0 U/mL = negative
• >3.0 = positive


Seronegativity does not exclude the diagnosis of NMO.1 Immunosuppressive therapy may result in negative results.