ACTIN (SMOOTH MUSCLE) ANTIBODY (ASMA)
General Information
HLAB/HOL Code: SMU
UPHSM LIS Test #: 26500
Schedule:
Testing Time: 2-3 Days
Testing Lab: Labcorp
UPHSM LIS Test #: 26500
Schedule:
Testing Time: 2-3 Days
Testing Lab: Labcorp
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 1.0 mL Serum (0.3 mL Minimum)
Temperature: Ambient
Tube Type: Serum
Collection Info:
Causes for Rejection: Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added
Temperature: Ambient
Tube Type: Serum
Collection Info:
Causes for Rejection: Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added
Methods
Enzyme-linked immunosorbent assay (ELISA)
Clinical Utilities
Use: Detection of antibodies aids in the diagnosis of autoimmune liver diseases such as autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC)
Limitations: Antiactin antibodies have been reported at low levels in 3% to 18% of sera from the general healthy population. The presence of immune complexes in the patient's sample may produce false positives in this assay. Not all smooth muscle positive samples will have actin antibodies.
Limitations: Antiactin antibodies have been reported at low levels in 3% to 18% of sera from the general healthy population. The presence of immune complexes in the patient's sample may produce false positives in this assay. Not all smooth muscle positive samples will have actin antibodies.
CPT Codes
83516
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
• Negative: 0-19
• Weak positive: 20-30
• Moderate to strong positive: >30
• Weak positive: 20-30
• Moderate to strong positive: >30
