PROTEIN ELECTROPHORESIS RANDOM URINE
General Information
HLAB/HOL Code: UPEP
UPHSM LIS Test #: 022510
Schedule:
Testing Time: 3-5 Days
Testing Lab: Labcorp
UPHSM LIS Test #: 022510
Schedule:
Testing Time: 3-5 Days
Testing Lab: Labcorp
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 20 mL
Temperature: Refrigerate
Tube Type: Urine-Random
Collection Info:
Collection: Collect first morning urine; mix well.
Temperature: Refrigerate
Tube Type: Urine-Random
Collection Info:
Collection: Collect first morning urine; mix well.
Specimen Acceptability
Cause for Rejection:
Preservative added
Preservative added
Methods
Electrophoresis on agarose media
Clinical Utilities
Use:
Evaluate myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight problems.
Limitations:
May not detect pathologic light chains due to insufficient sensitivity. Should be followed with immunoelectrophoretic or immunofixation study performed on concentrated urine. Optimal specimen when looking for a free monoclonal light chain (Bence Jones protein) is a 24-hour collection.
Evaluate myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight problems.
Limitations:
May not detect pathologic light chains due to insufficient sensitivity. Should be followed with immunoelectrophoretic or immunofixation study performed on concentrated urine. Optimal specimen when looking for a free monoclonal light chain (Bence Jones protein) is a 24-hour collection.
CPT Codes
84156; 84166
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
An Interpretive Report will be Provided.
