UROPORPHYRINOGEN III SYNTHASE (CO-SYNTHASE) (UPG III S) ERYTHROCYTES
General Information
HLAB/HOL Code: UPS
UPHSM LIS Test #: 026950
Schedule:
Testing Time: 7-14 Days
Testing Lab: Mayo
UPHSM LIS Test #: 026950
Schedule:
Testing Time: 7-14 Days
Testing Lab: Mayo
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: Full tube
Temperature: Refrigerate
Tube Type: Whole Blood (Heparin)
Collection Info:
ORDERING GUIDANCE
This test is most appropriately used for pediatric patients.
This test measures uroporphyrinogen (UPG) III synthase to confirm congenital erythropoietic porphyria, which is typically seen in early infancy. It does not measure UPG I synthase (also known as porphobilinogen deaminase), the enzyme deficient in acute intermittent porphyria (AIP). For AIP (and UPG I synthase), order PBGD_ / Porphobilinogen Deaminase, Whole Blood.
NECESSARY INFORMATION
1. Include a list of medications the patient is currently taking.
2. Date of transfusion, if performed
SPECIMEN REQUIRED
Patient Preparation: Patient should abstain from alcohol for 24 hours.
Container/Tube: Green top (heparin)
Specimen Volume: Full tube
Collection Instructions: Immediately place specimen on wet ice.
Temperature: Refrigerate
Tube Type: Whole Blood (Heparin)
Collection Info:
ORDERING GUIDANCE
This test is most appropriately used for pediatric patients.
This test measures uroporphyrinogen (UPG) III synthase to confirm congenital erythropoietic porphyria, which is typically seen in early infancy. It does not measure UPG I synthase (also known as porphobilinogen deaminase), the enzyme deficient in acute intermittent porphyria (AIP). For AIP (and UPG I synthase), order PBGD_ / Porphobilinogen Deaminase, Whole Blood.
NECESSARY INFORMATION
1. Include a list of medications the patient is currently taking.
2. Date of transfusion, if performed
SPECIMEN REQUIRED
Patient Preparation: Patient should abstain from alcohol for 24 hours.
Container/Tube: Green top (heparin)
Specimen Volume: Full tube
Collection Instructions: Immediately place specimen on wet ice.
Specimen Acceptability
REJECT DUE TO:
Gross hemolysis: Reject
Gross hemolysis: Reject
Methods
High-Performance Liquid Chromatography (HPLC)
Clinical Utilities
Diagnosis of congenital erythropoietic porphyria
This test is not useful for diagnosis of acute intermittent porphyria (AIP).
This test is not useful for diagnosis of acute intermittent porphyria (AIP).
CPT Codes
82657
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.