COXSACKIE A VIRUS ANTIBODY PROFILE IGG
General Information
HLAB/HOL Code: COXA
UPHSM LIS Test #: 026338
Schedule:
Testing Time: 1-4 Days
Testing Lab: Labcorp
UPHSM LIS Test #: 026338
Schedule:
Testing Time: 1-4 Days
Testing Lab: Labcorp
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 1.0 mL
Temperature: Refrigerated
Tube Type: Serum
Collection Info:
Minimum Volume: 0.5 mL (Note: This volume does not allow for repeat testing.)
Container: Gel-barrier tube or red-top tube
Temperature: Refrigerated
Tube Type: Serum
Collection Info:
Minimum Volume: 0.5 mL (Note: This volume does not allow for repeat testing.)
Container: Gel-barrier tube or red-top tube
Specimen Acceptability
Cause for Rejection:
Microbially-contaminated or heat-treated specimen; specimen containing particulate matter; grossly hemolyzed, lipemic, or icteric samples
Microbially-contaminated or heat-treated specimen; specimen containing particulate matter; grossly hemolyzed, lipemic, or icteric samples
Methods
Indirect fluorescent antibody (IFA)
Clinical Utilities
Use: This assay uses indirect immunofluorescence to determine IgG titers to Coxsackie A serotypes A7, A9, A16, and A24. Recent infections of Coxsackie viruses are characterized by elevated titers of IgG and IgM.
Limitations: A positive test result does not necessarily indicate current or recent infection as antibodies to Coxsackie species can be detected in uninfected individuals due to moderate passive exposure to infected hosts. It is, therefore, crucial that results from all Coxsackie A serologies correlate with the clinical history of the patient and all other data available to the physician. Samples collected at the early stage of infection (primarily in children) may not yield detectable antibodies. If a recent infection is suspected, a second specimen should be collected 10-20 days following the initial collection and tested.
Limitations: A positive test result does not necessarily indicate current or recent infection as antibodies to Coxsackie species can be detected in uninfected individuals due to moderate passive exposure to infected hosts. It is, therefore, crucial that results from all Coxsackie A serologies correlate with the clinical history of the patient and all other data available to the physician. Samples collected at the early stage of infection (primarily in children) may not yield detectable antibodies. If a recent infection is suspected, a second specimen should be collected 10-20 days following the initial collection and tested.
CPT Codes
86658x4
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
See Report
