IMIPRAMINE AND DESIPRAMINE SERUM
General Information
HLAB/HOL Code: IMIP
UPHSM LIS Test #: 026537
Schedule:
Testing Time: 3-5 Days
Testing Lab: Mayo
UPHSM LIS Test #: 026537
Schedule:
Testing Time: 3-5 Days
Testing Lab: Mayo
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 1.0 mL
Temperature: Refrigerate
Tube Type: Serum
Collection Info:
Collection Container/Tube: Red top (Serum gel/SST are NOT acceptable)
Collection Instructions:
1. Collect specimen immediately before next scheduled dose (minimum 12 hours after last dose).
2. Centrifuge and aliquot serum into plastic vial. Serum must be separated from cells within 2 hours of collection.
Temperature: Refrigerate
Tube Type: Serum
Collection Info:
Collection Container/Tube: Red top (Serum gel/SST are NOT acceptable)
Collection Instructions:
1. Collect specimen immediately before next scheduled dose (minimum 12 hours after last dose).
2. Centrifuge and aliquot serum into plastic vial. Serum must be separated from cells within 2 hours of collection.
Specimen Acceptability
REJECT DUE TO:
Gross hemolysis: Reject
Gross lipemia: Reject
Gross icterus: Reject
Gross hemolysis: Reject
Gross lipemia: Reject
Gross icterus: Reject
Methods
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Clinical Utilities
Monitoring imipramine and desipramine concentrations during therapy
Evaluating potential imipramine and desipramine toxicity
The test may also be useful to evaluate patient compliance
Evaluating potential imipramine and desipramine toxicity
The test may also be useful to evaluate patient compliance
CPT Codes
80335
G0480 (if appropriate)
G0480 (if appropriate)
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
IMIPRAMINE and DESIPRAMINE
Total therapeutic concentration: 175-300 ng/mL
Total toxic concentration: > or = 300 ng/mL
DESIPRAMINE ONLY
Total therapeutic concentration: 100-300 ng/mL
Total toxic concentration: >= 300 ng/mL
Total therapeutic concentration: 175-300 ng/mL
Total toxic concentration: > or = 300 ng/mL
DESIPRAMINE ONLY
Total therapeutic concentration: 100-300 ng/mL
Total toxic concentration: >= 300 ng/mL