METANEPHRINES FRACTIONATED QUANTITATIVE 24-HOUR URINE
General Information
HLAB/HOL Code: MET
UPHSM LIS Test #: 4684
Schedule:
Testing Time:
Testing Lab: Labcorp
UPHSM LIS Test #: 4684
Schedule:
Testing Time:
Testing Lab: Labcorp
Specimen Info
Only 1 specimen type required, unless otherwise specified
Volume: 10 mL
Temperature: Ambient
Tube Type: 24 hour urine
Collection Info:
Minimum Volume: 2.5 mL aliquot (Note: This volume does not allow for repeat testing.)
Container: Plastic urine container with no preservative or 6N HCl
Collection: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Label container with patient's name, date and time collection started, and date and time collection finished. Measure and record total 24-hour volume. Mix well; send aliquot.
Temperature: Ambient
Tube Type: 24 hour urine
Collection Info:
Minimum Volume: 2.5 mL aliquot (Note: This volume does not allow for repeat testing.)
Container: Plastic urine container with no preservative or 6N HCl
Collection: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Label container with patient's name, date and time collection started, and date and time collection finished. Measure and record total 24-hour volume. Mix well; send aliquot.
Methods
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Clinical Utilities
Evaluation of catecholamine-secreting tumors of the adrenal medulla (pheochromocytomas) and extra-adrenal sympathetic and parasympathetic paragangliomas.
CPT Codes
83835
* The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding
is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Reference Range
Pediatric and adults:
Normetanephrine (normotensive):
• 0-2 years: not established
• 3-8 years: 13-252 μg/24 hours
• 9-12 years: 32-346 μg/24 hours
• 13-17 years: 63-402 μg/24 hours
• >17 years: 82-500 μg/24 hours
Normetanephrine (hypertensive):
2 >17 years: 110-1050 μg/24 hours
Metanephrine (normotensive):
• 0-2 years: not established
• 3-8 years: 5-113 μg/24 hours
• 9-12 years: 21-154 μg/24 hours
• 13-17 years: 32-167 μg/24 hours
• >17 years: 45-290 μg/24 hours
Metanephrine (hypertensive):
2 >17 years: 35-460 μg/24 hours
Normetanephrine (normotensive):
• 0-2 years: not established
• 3-8 years: 13-252 μg/24 hours
• 9-12 years: 32-346 μg/24 hours
• 13-17 years: 63-402 μg/24 hours
• >17 years: 82-500 μg/24 hours
Normetanephrine (hypertensive):
2 >17 years: 110-1050 μg/24 hours
Metanephrine (normotensive):
• 0-2 years: not established
• 3-8 years: 5-113 μg/24 hours
• 9-12 years: 21-154 μg/24 hours
• 13-17 years: 32-167 μg/24 hours
• >17 years: 45-290 μg/24 hours
Metanephrine (hypertensive):
2 >17 years: 35-460 μg/24 hours